Has there ever been a 10–1 in the Brasileirão?

Yes, 1 time.

The only time: February 9, 1983, Corinthians beat Tiradentes (Corinthians 10–1 Tiradentes).

Nearby scores

1. 11–0 Never
2. 11–1 Never
3. 11–2 Never
4. 10–0 Never
5. 10–1 1 time
6. 10–2 Never
7. 9–0 1 time
8. 9–1 Never
9. 9–2 1 time