Has there ever been a 10–0 in the Serie A?

Yes, 1 time.

The only time: May 9, 1948, Torino FC beat Alessandria (Torino FC 10–0 Alessandria).

Nearby scores

1. 11–0 Never
2. 11–1 Never
3. 10–0 1 time
4. 10–1 Never
5. 9–0 4 times
6. 9–1 8 times