Has there ever been a 8–1 in the Serie A?

Yes, 4 times.

The first time: November 19, 1933, Juventus FC beat Genova 1893 (Juventus FC 8–1 Genova 1893).

The last time: October 16, 1955, SSC Napoli beat Pro Patria (SSC Napoli 8–1 Pro Patria), 71 years ago.

Home wins: 4. Away wins: 0.

Nearby scores

1. 9–0 4 times
2. 9–1 8 times
3. 9–2 2 times
4. 8–0 14 times
5. 8–1 4 times
6. 8–2 6 times
7. 7–0 29 times
8. 7–1 34 times
9. 7–2 15 times

All games

1. October 16, 1955 SSC Napoli 8–1 Pro Patria
2. January 4, 1948 AC Milan 8–1 AS Bari
3. March 18, 1934 Internazionale 8–1 Lazio
4. November 19, 1933 Juventus FC 8–1 Genova 1893