Has there ever been a 10–1 in all competitions?

Yes, 21 times.

The first time: October 15, 1892, Manchester United beat Wolverhampton Wanderers (Manchester United 10–1 Wolverhampton Wanderers) · Premier League.

The last time: February 9, 1983, Corinthians beat Tiradentes (Corinthians 10–1 Tiradentes) · Brasileirão, 43 years ago.

Home wins: 16. Away wins: 5.

Nearby scores

1. 11–0 5 times
2. 11–1 6 times
3. 11–2 3 times
4. 10–0 25 times
5. 10–1 21 times
6. 10–2 7 times
7. 9–0 63 times
8. 9–1 53 times
9. 9–2 33 times

All games

1. February 9, 1983 Corinthians 10–1 Tiradentes · Brasileirão
2. August 11, 1974 River Plate 10–1 Huracán (San Rafael) · Primera Argentina
3. December 26, 1963 Fulham 10–1 Ipswich Town · Premier League
4. May 8, 1960 Sittardia 1–10 Sportclub Enschede · Eredivisie
5. January 4, 1959 Real Madrid 10–1 UD Las Palmas · La Liga
6. December 8, 1957 Lille OSC 10–1 AS Béziers · Ligue 1
7. September 23, 1951 Athletic Bilbao 10–1 Real Zaragoza · La Liga
8. November 5, 1950 Deportivo La Coruña 10–1 UE Lleida · La Liga
9. October 23, 1949 Celta de Vigo 10–1 Gimnàstic de Tarragona · La Liga
10. September 11, 1949 FC Barcelona 10–1 Gimnàstic de Tarragona · La Liga
11. September 21, 1947 Atlante 1–10 León · Liga MX
12. March 31, 1946 España 10–1 Monterrey · Liga MX
13. September 5, 1943 Boca Juniors 10–1 Chacarita Juniors · Primera Argentina
14. April 15, 1938 Wolverhampton Wanderers 10–1 Leicester City · Premier League
15. December 13, 1930 Huddersfield Town 10–1 Blackpool · Premier League
16. April 5, 1914 Comercio 1–10 Huracán · Primera Argentina
17. September 7, 1913 San Isidro 10–1 Olivos · Primera Argentina
18. August 18, 1912 Belgrano Athletic 10–1 River Plate · Primera Argentina
19. October 17, 1909 Argentino de Quilmes 1–10 Estudiantes de Buenos Aires · Primera Argentina
20. August 9, 1903 Flores Athletic 1–10 Lomas Athletic · Primera Argentina
21. October 15, 1892 Manchester United 10–1 Wolverhampton Wanderers · Premier League