Has there ever been a 10–4 in the Premier League?

Yes, 1 time.

The only time: October 11, 1958, Tottenham Hotspur beat Everton (Tottenham Hotspur 10–4 Everton).

Nearby scores

1. 11–3 Never
2. 11–4 Never
3. 11–5 Never
4. 10–3 2 times
5. 10–4 1 time
6. 10–5 Never
7. 9–3 3 times
8. 9–4 Never
9. 9–5 Never